Clysmatica nova was one of the first books to discuss blood transfusion and the intravenous injection of drugs. This greatly expanded second edition included plates that depict the transfusion of blood from animal to animal, man to man, and animal to man.

Elsholtz, Johann Sigismund, 1623-1688. Clysmatica nova (Coloniae Brandenburgicae : Ex officina Georgi Schultzi impensis Danielis Reichelii, 1667)

Qdd 46a (Historical Medical Library of the College of Physicians of Philadelphia)